Cryoglobins are unusual proteins that precipitate out of solution at low
temperatures and reversibly re-dissolve on warming. Their presence is
associated with:
- Auto-immune diseases, including:
- Poststreptococcal glomerulonephritis
- Rheumatoid arthritis
- Lupus
- Sjoegren's syndrome
- Polyarteritis nodosum
- Infectious illnesses, including:
- Mononucleosis
- Syphilis
- Cytomegalovirus
- Leprosy
- Sarcoidosis
- Malignancies, specifically:
- Multiple myeloma
- Chronic lymphocytic leukemia
- Lymphosarcoma
- Liver disease, hemolytic disease, and ulcerative colitis
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Normal Values*
*These are general values taken from a variety of
sources. The actual normal values may vary from lab to lab and from one
type of testing protocol to another.
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