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PTT detects nearly all abnormalities in clotting, due to deficiencies in
clotting factors or circulating anticoagulants.
It is frequently used to monitor heparin therapy.
A modification of the test, "Activated PTT," or APTT, is
basically the same as PTT, but is slightly more sensitive.
Prolonged PTT is associated with:
- Liver disease
- Vitamin K deficiency
- Anticoagulant (Coumarin, Coumadin, Heparin) therapy
- DIC
- Hemophilia
Therapeutic Range (Heparin Therapy)
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Normal Values*
| PTT |
30-45 seconds |
| APTT |
16-25 seconds |
|
Therapeutic Range on oral anticoagulants
|
2-2.5 times normal |
*These are general values taken from a variety of
sources. The actual normal values may vary from lab to lab and from one
type of testing protocol to another.
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