SGOT (Serum Glutamic-Oxaloacetic Transaminase)
AST (Aspartate Amio Transferase)
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SGOT (AST) is an enzyme found in all tissues with high metabolic activity,
but primarily:
- Heart
- Liver
- Skeletal Muscle
- Kidney
- Brain
- Pancreas
- Spleen
- Lung
Elevations found in:
- Any traumatic injury to any of these structures.
- Any disease affecting one of these structures.
- Acute myocardial infarction (4-10X normal)
- Liver disease (10-100X normal)
- Once elevated, the SGOT remains elevated for several days, if the
injury is acute.
- If there is on-going injury, the SGOT will remain elevated
indefinitely.
Decreased amounts found in:
- Uncontrolled diabetes with acidosis
- Beriberi
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Normal Values*
Men |
8-20 µ/L at 30º |
Women |
6-18 µ/L at 30º |
Children |
25-75 µ/L at 30º |
*These are general values taken from a variety of
sources. The actual normal values may vary from lab to lab and from one
type of testing protocol to another.
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Source:
Operational Medicine 2001, Health
Care in Military Settings, NAVMED P-5139, May 1, 2001, Bureau
of Medicine and Surgery, Department of the Navy, 2300 E Street NW, Washington,
D.C., 20372-5300 |