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Uric acid is a breakdown product of cell nuclei.
Two-thirds are excreted in the urine and one-third in the stool.
Changes in serum uric acid levels may be caused by:
- Increased production of urates
- Decreased excretion of urates
Uric Acid levels may rise in the presence of:
- Renal failure
- Gout
- Cancer
- Pre-eclampsia
- Starvation
- Shock
- Alcoholism
- Diabetic ketoacidosis
- Hemolysis
- Trauma
Uric Acid levels may fall in the presence of:
- Pregnancy
- Wilson's Disease
- Fanconi Syndrom
- Uricosuric drugs (allopurinol, sulfinpyrazone, probenecid)
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Normal Values*
| Men |
3.5-7.2 mg/dl |
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Women
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1.5-6.0 mg/dl |
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Pregnancy
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1.2-4.5 |
*These are general values taken from a variety of
sources. The actual normal values may vary from lab to lab and from one
type of testing protocol to another.
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