Chlorpheniramine and Pseudoephedrine (Deconamine, various)

Category:

• Miscellaneous

Description:

• Antihistamine and sympathomimetic combination

Indications:

• allergic rhinitis

• common cold

• nasal congestion

Contraindications:

• Severe hypertension, concurrent MAOI use, ischemic heart disease

Precautions:

• Hypertension, prostatic hypertrophy, hyperthyroidism

• Diabetes mellitus, peripheral vascular disease

• Glaucoma

Adverse Reactions (Side Effects):

• drowsiness

• hyperexcitability

• nervousness, insomnia, dizziness

Dosage:

Administered orally (tablet, capsule, sustained release tablet, sustained release capsule, syrup

• Adult: 

  • (extended-release capsule or tablet): PO 1 tablet or capsule every 12 hours

  • (nonextended-release tablets): PO 1 tablet every 4-6 hours

• Note: Base dose on pseudoephedrine:

  • Adult: PO 60mg q 4-6 hours; 

  • PO SUS REL 120mg every 12 hours or 240mg once daily