Mineral Oil (Agoral, Milkinol, Petrogalar Plain)

Category:

• Miscellaneous

Description:

• Lubricant laxative

Indications:

• Bowel evacuation

• Constipation

Contraindications:

• Appendicitis, acute surgical abdomen, intestinal obstruction

• Undiagnosed abdominal pain

Precautions:

• Anal seepage

• Lipid pneumonitis

Adverse Reactions (Side Effects):

• GI: griping, diarrhea, nausea, vomiting, perianal irritation, abdominal cramps

• CNS: dizziness, syncope

Dosage:

Administered orally and rectally

• Adult and children >11 years: PO 15-45ml daily; PR 120ml daily

• Child 5-11 years: PO 5-15ml daily. Should not use longer than 1 week. PR 30-60ml as a single dose

Drug interactions:

• Lipid-soluble vitamins: absorption of vitamins can be decreased with prolonged administration of mineral oil

• Surfactants (e.g., docusate): can facilitate absorption of mineral oil, possibly increasing toxicity