Nitroglycerin Lingual Aerosal (Nitrostat)

Category:

• Miscellaneous

Description:

• Antianginal (organic nitrate)

Indications:

• Acute angina

• Angina prophylaxis

Contraindications:

• Postural hypotension, early MI, closed-angle glaucoma, head trauma, cerebral hemorrhage

• Increased intracranial pressure, hypotension or uncorrected hypovolemia

Precautions:

• Pregnancy category C; use for angina during pregnancy without fetal harm has been reported

• Hypertrophic cardiomyopathy, children, glaucoma

Adverse Reactions (Side Effects):

• CNS: agitation, apprehension, confusion, dizziness, dyscoordination, insomnia, nightmares, restlessness, vertigo, weakness

• CV: atrial fibrillation, collapse, crescendo angina, dysrhythmias, postural hypotension, PVC’s, rebound hypertension, retrosternal discomfort, syncope, tachycardia

• EENT: blurred vision

• HEME: hemolytic anemia, methemoglobinemia

• SKIN: Cutaneous vasodilation with flushing, exfoliative dermatitis

Dosage:

Administered orally (aerosol)

• Adult:            

  • TRANSLINGUAL 1-2 sprays under tongue every 3-5 minutes for max of 3 doses in 15 minutes; may also use prophylactically 5-10 minutes prior to activities that provoke angina attack