Vulvar vestibulitis is a condition of uncertain cause, characterized by
pain and burning in specific sites on the vulva.
The pain is most noticeable during intercourse and is very consistent, both in
character and location.
The pain and tenderness is distributed in a U-shaped pattern around the introitus and
includes the hymeneal remnants and up to 1 cm of skin exterior to the hymen. Visually, the
tender areas are reddened and touching them gently with a cotton-tipped applicator will
duplicate the pain they experience during intercourse (a positive "Q-Tip Test").
Biopsy of these tender areas will show a generalized inflammatory pattern of non-specific
etiology.
Some women with vestibulitis indicate they have always felt this discomfort during
intercourse. Others seem to have acquired the condition. They have painless intercourse
initially, and later develop the painful intercourse so characteristic of this condition.
The diagnosis is based on the physical examination, with persistent areas of tenderness
to touch, located in the U-shaped area surrounding the hymenal ring. Biopsy is neither
necessary nor often done.
Treatment is problematic. Antibiotics, anti-fungals, anti-virals, estrogens, and
steroids are often used and are often found to be ineffective. Antioxalates (used with the
theory that oxalates provoke a skin reaction in this area) are promoted by some, but
randomized studies demonstrate them to be no better than placebo.
Several studies have demonstrated the efficacy of surgical excision of the affected
area (perineoplasty) in selected cases.
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